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Time-Point Dependent Activation of Autophagy and the UPS in SOD1G93A Mice Skeletal Muscle

Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease characterized by a selective loss of motor neurons together with a progressive muscle weakness. Albeit the pathophysiological mechanisms of the disease remain unknown, growing evidence suggests that skeletal muscle can be a tar...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Oliván, Sara, Calvo, Ana Cristina, Gasco, Samanta, Muñoz, María Jesús, Zaragoza, Pilar, Osta, Rosario
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4526523/
https://ncbi.nlm.nih.gov/pubmed/26244336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134830
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