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Modulation of inflammatory mediators in the trigeminal ganglion by botulinum neurotoxin type A: an organ culture study

BACKGROUND: Onabotulinumtoxin type A (BoNT-A) has been found to reduce pain in chronic migraine. The aim of the present study was to ask if BoNT-A can interact directly on sensory mechanisms in the trigeminal ganglion (TG) using an organ culture method. METHODS: To induce inflammation, rat TGs were...

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Detalhes bibliográficos
Publicado no:J Headache Pain
Main Authors: Edvinsson, Jacob, Warfvinge, Karin, Edvinsson, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Milan 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4526514/
https://ncbi.nlm.nih.gov/pubmed/26245187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10194-015-0555-z
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