Long-term proliferating early pre B cell lines and clones with the potential to develop to surface Ig-positive, mitogen reactive B cells in vitro and in vivo.

Cell lines and clones were established from PB76-positive mouse fetal liver at day 13 and 14 of gestation, which proliferated with division times of a day in serum-substituted cultures under the stimulatory influence of adherent stromal cells and the cytokine IL-7 for periods longer than half a year...

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Bibliografiske detaljer
Udgivet i:EMBO J
Main Authors: Rolink, A, Kudo, A, Karasuyama, H, Kikuchi, Y, Melchers, F
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1991
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC452650/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1991449/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1991.tb07953.x
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