Analysis of the anti-proliferative and the pro-apoptotic efficacy of Syk inhibition in multiple myeloma

BACKGROUND: Multiple myeloma (MM) is a clonal B cell malignancy characterized by proliferation of malignant plasma cells in the bone marrow. Despite high-dose melphalan therapy with autologous stem cell transplantation (ASCT) and the introduction of immunomodulatory drugs like bortezomib or lenalido...

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Detalhes bibliográficos
Publicado no:Exp Hematol Oncol
Main Authors: Koerber, Ruth-Miriam, Held, Stefanie Andrea Erika, Heine, Annkristin, Kotthoff, Philipp, Daecke, Solveig Nora, Bringmann, Anita, Brossart, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4526421/
https://ncbi.nlm.nih.gov/pubmed/26251761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40164-015-0016-z
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