Pre-diagnostic obesity and physical inactivity are associated with shorter telomere length in prostate stromal cells

Obesity and inactivity have been with associated advanced stage prostate cancer, and poor prostate cancer outcomes, though the underlying mechanism(s) is unknown. To determine if telomere shortening, which has been associated with lethal prostate cancer, may be a potential underlying mechanism, we p...

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Pubblicato in:Cancer Prev Res (Phila)
Autori principali: Joshu, Corinne E, Peskoe, Sarah B, Heaphy, Christopher M, Kenfield, Stacey A, Van Blarigan, Erin L, Mucci, Lorelei A, Giovannucci, Edward L, Stampfer, Meir J, Yun, GhilSuk, Lee, Thomas K, Hicks, Jessica L, De Marzo, Angelo M, Meeker, Alan K, Platz, Elizabeth A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4526348/
https://ncbi.nlm.nih.gov/pubmed/25990087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-15-0097
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