The Impact of DNA Input Amount and DNA source on the Performance of Whole-Exome Sequencing in Cancer Epidemiology

BACKGROUND: Whole-exome sequencing (WES) has recently emerged as an appealing approach to systematically study coding variants. However, the requirement for a large amount of high-quality DNA poses a barrier that may limit its application in large cancer epidemiologic studies. We evaluated the perfo...

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Pubblicato in:Cancer Epidemiol Biomarkers Prev
Autori principali: Zhu, Qianqian, Hu, Qiang, Shepherd, Lori, Wang, Jianmin, Wei, Lei, Morrison, Carl, Conroy, Jeffrey M., Glenn, Sean T., Davis, Warren, Kwan, Marilyn L., Ergas, Isaac J., Roh, Janise M., Kushi, Lawrence H., Ambrosone, Christine B., Liu, Song, Yao, Song
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4526319/
https://ncbi.nlm.nih.gov/pubmed/25990554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-15-0205
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