Mammalian nuclei contain foci which are highly enriched in components of the pre-mRNA splicing machinery.

The organization of the major snRNP particles in mammalian cell nuclei has been analysed by in situ labelling using snRNA-specific antisense probes made of 2'-OMe RNA. U3 snRNA is exclusively detected in the nucleolus while all the spliceosomal snRNAs are found in the nucleoplasm outside of nuc...

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Main Authors: Carmo-Fonseca, M, Tollervey, D, Pepperkok, R, Barabino, S M, Merdes, A, Brunner, C, Zamore, P D, Green, M R, Hurt, E, Lamond, A I
Format: Artigo
Sprog:Inglês
Udgivet: 1991
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC452630/
https://ncbi.nlm.nih.gov/pubmed/1824936
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