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Synthesis and Immunological Study of α-2,9-Oligosialic Acid Conjugates as Anti-Group C Meningitis Vaccines
α-2,9-Di-, tri-, tetra-, and pentasialic acids were prepared and conjugated with a carrier protein. The resultant glycoconjugates elicited robust T cell-mediated immunity in mice. α-2,9-Trisialic acid was identified as a promising antigen for developing glycoconjugate vaccines against group C Neisse...
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| 出版年: | Chem Commun (Camb) |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4526240/ https://ncbi.nlm.nih.gov/pubmed/25973942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5cc01794g |
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