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TNF induces c-fos via a novel pathway requiring conversion of arachidonic acid to a lipoxygenase metabolite.

Tumour necrosis factor (TNF), a lymphokine released by activated macrophages, has diverse effects on a wide variety of cell types. TNF exerts these effects via specific cell surface receptors; however little is known of the biochemical events that ensue. We have shown that TNF rapidly induces the pr...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Haliday, E M, Ramesha, C S, Ringold, G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC452618/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1899225/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1991.tb07926.x
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