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Therapeutic Targeting of Tumor Suppressor Genes
Carcinogenesis is a multistep process attributable to both gain-of-function mutations in oncogenes and loss-of-function mutations in tumor suppressor genes. Currently, most molecular targeted therapies are inhibitors of oncogenes, because inactivated tumor suppressor genes have proven harder to “dru...
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| 發表在: | Cancer |
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| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4526158/ https://ncbi.nlm.nih.gov/pubmed/25557041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.29140 |
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