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Identification of the site of interaction of the dihydropyridine channel blockers nitrendipine and azidopine with the calcium-channel alpha 1 subunit.

The dihydropyridine binding site of the rabbit skeletal muscle calcium channel alpha 1 subunit was identified using tritiated azidopine and nitrendipine as ligands. The purified receptor complex was incubated either with azidopine or nitrenidpine at an alpha 1 subunit to ligand ratio of 1:1. The sam...

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Publicat a:EMBO J
Autors principals: Regulla, S, Schneider, T, Nastainczyk, W, Meyer, H E, Hofmann, F
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1991
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC452609/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1846597/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1991.tb07919.x
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