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Performance of exome sequencing for pharmacogenomics

AIM: We present the potential false-negative rate of exome sequencing for the detection of pharmacogenomic variants. MATERIALS & METHODS: Depth of coverage of 1928 pharmacogenomically relevant variant positions was ascertained from 62 exome-sequenced samples. RESULTS: Approximately 14% of the 19...

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Dades bibliogràfiques
Publicat a:Per Med
Autors principals: Londin, Eric R, Clark, Peter, Sponziello, Marialuisa, Kricka, Larry J, Fortina, Paolo, Park, Jason Y
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4526024/
https://ncbi.nlm.nih.gov/pubmed/26257813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/PME.14.77
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