Detection of t(12;14)(p13;q32) in a patient with IGH-CCND1 negative mantle cell lymphoma resembling ultra-high risk chronic lymphocytic leukemia

t(12;14)(p13;q32) is a rare recurrent chromosomal translocation, which has only been identified in a small subgroup of mantle cell lymphoma (MCL) without typical t(11;14)(q13;q32). This rearrangement causes aberrant over-expression of cyclin D2 (CCND2), which disrupts the normal cell cycle. Here we...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Pathol
Main Authors: Miao, Yi, Wang, Rong, Fan, Lei, Qiu, Hairong, Wu, Yujie, Chen, Yaoyu, Xu, Wei, Li, Jianyong
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2015
Assuntos:
Case Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4525993/
https://ncbi.nlm.nih.gov/pubmed/26261659
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