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Effects of targeted nano-delivery systems combined with hTERT-siRNA and Bmi-1-siRNA on MCF-7 cells

The aim of this study was to evaluate the efficiency of a targeted siRNA nano-delivery system to silence the expression of Bmi-1 and hTERT, and to verify the toxicity of this delivery system in MCF-7 breast cancer cells. The most effective Bmi-1 siRNA and hTERT siRNA sequences were selected using RT...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Clin Exp Pathol
Hauptverfasser: Liu, Lei, Li, Huixiang, Zhang, Min, Lv, Xinquan
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4525883/
https://ncbi.nlm.nih.gov/pubmed/26261549
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