Formononetin sensitizes glioma cells to doxorubicin through preventing EMT via inhibition of histone deacetylase 5

Chemoresistance is a major obstacle to successful chemotherapy for glioma. Formononetin is a novel herbal isoflavonoid isolated from Astragalus membranaceus and possesses antitumorigenic properties. In the present study, we investigated the anti-proliferative effects of formononetin on human glioma...

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Bibliographic Details
Published in:Int J Clin Exp Pathol
Main Authors: Liu, Quan, Sun, Yan, Zheng, Jie-Min, Yan, Xian-Lei, Chen, Hong-Mou, Chen, Jia-Kang, Huang, He-Qing
Format: Artigo
Language:Inglês
Published: e-Century Publishing Corporation 2015
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4525853/
https://ncbi.nlm.nih.gov/pubmed/26261519
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