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A modified procedure for the palladium catalyzed borylation/Suzuki-Miyaura cross-coupling of aryl and heteroaryl halides utilizing bis-boronic acid

A modified Pd-catalyzed method of forming aryl- and heteroarylboron species and a two-step, one-pot borylation/Suzuki-Miyaura cross coupling using the atom economical tetrahydroxydiboron (bis-boronic acid, BBA) is reported. By using ethylene glycol as an additive, the new method results in increased...

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Detalhes bibliográficos
Publicado no:Tetrahedron
Main Authors: Molander, Gary A., Trice, Sarah L. J., Tschaen, Brittany
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4525720/
https://ncbi.nlm.nih.gov/pubmed/26257439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2015.04.026
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