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Role of the Midbody Matrix in Cytokinesis: RNAi and Genetic Rescue Analysis of the Mammalian Motor Protein CHO1

CHO1 is a kinesin-like motor protein essential for cytokinesis in mammalian cells. To analyze how CHO1 functions, we established RNAi and genetic rescue assays. CHO1-depleted cells reached a late stage of cytokinesis but fused back to form binucleate cells because of the absence of the midbody matri...

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Bibliografische gegevens
Hoofdauteurs: Matuliene, Jurgita, Kuriyama, Ryoko
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Cell Biology 2004
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC452566/
https://ncbi.nlm.nih.gov/pubmed/15075367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-12-0888
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