High-affinity reactions between antigen-specific T-cell receptors and peptides associated with allogeneic and syngeneic major histocompatibility complex class I proteins.

We report here that the intrinsic affinities of the antigen-specific T-cell receptors (TCR) of two unrelated CD8+ T-cell clones for their respective peptide-major histocompatibility complex (MHC) ligands are higher than the values generally thought to prevail for TCR. The TCR of one clone (2C) binds...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Sykulev, Y, Brunmark, A, Tsomides, T J, Kageyama, S, Jackson, M, Peterson, P A, Eisen, H N
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45256/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7972089/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.24.11487
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