High-dose ascorbate with low-dose amphotericin B attenuates severity of disease in a model of the reappearance of candidemia during sepsis in the mouse

Amphotericin B (Ampho B) is a fungicidal drug that causes cell wall injury. Pharmacological ascorbate induces the extracellular prooxidants, which might enter the Ampho B-induced cell wall porosity and act synergistically. We tested low-dose Ampho B with a short course of pharmacological ascorbate u...

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Bibliografski detalji
Izdano u:Am J Physiol Regul Integr Comp Physiol
Glavni autori: Leelahavanichkul, Asada, Somparn, Poorichaya, Bootprapan, Tanabodee, Tu, Hongbin, Tangtanatakul, Pattarin, Nuengjumnong, Ratchanok, Worasilchai, Navaporn, Tiranathanagul, Khajohn, Eiam-ong, Somchai, Levine, Mark, Chinampon, Ariya, Srisawat, Nattachai
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2015
Teme:
Physical Activity and Inactivity
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4525325/
https://ncbi.nlm.nih.gov/pubmed/25994956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00238.2014
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