Epstein-Barr virus latent membrane protein (LMP1) is not sufficient to maintain proliferation of B cells but both it and activated CD40 can prolong their survival.

Epstein-Barr virus (EBV) infects human primary B lymphocytes and induces and maintains proliferation of these cells efficiently in vitro. Mutants of Epstein-Barr virus which express EBV nuclear antigen 2 (EBNA2) in a conditional fashion allow dissection of individual contributions of viral genes to...

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Vydáno v:EMBO J
Hlavní autoři: Zimber-Strobl, U, Kempkes, B, Marschall, G, Zeidler, R, Van Kooten, C, Banchereau, J, Bornkamm, G W, Hammerschmidt, W
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 1996
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC452532/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9003782/
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