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Type 1 Insulin-Like Growth Factor Receptor/Insulin Receptor Substrate 1 Signaling Confers Pathogenic Activity on Breast Tumor Cells Lacking REST

Loss of repressor element 1 silencing transcription factor (REST) occurs in 20% of breast cancers and correlates with a poor patient prognosis. However, the molecular basis for enhanced malignancy in tumors lacking REST (RESTless) is only partially understood. We used multiplatform array data from t...

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Publicat a:Mol Cell Biol
Autors principals: Meyer, Kassondra, Albaugh, Brittany, Schoenike, Barry, Roopra, Avtar
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4525306/
https://ncbi.nlm.nih.gov/pubmed/26100015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01149-14
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