Analysis of mammalian 20S proteasome biogenesis: the maturation of beta-subunits is an ordered two-step mechanism involving autocatalysis.

Maturation of eukaryotic 20S proteasomes involves the processing of beta-subunits by limited proteolysis. To study the processing mechanism we analysed different point mutations of the beta-subunit LMP2 in transfected human T2 cells. Here we show that the presence of the intact Gly-1Thr1 consensus m...

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Bibliografische gegevens
Hoofdauteurs: Schmidtke, G, Kraft, R, Kostka, S, Henklein, P, Frömmel, C, Löwe, J, Huber, R, Kloetzel, P M, Schmidt, M
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1996
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC452515/
https://ncbi.nlm.nih.gov/pubmed/9003765
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