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Sensitizing soluble guanylyl cyclase to become a highly CO-sensitive enzyme.

It took at least a decade to realize that the toxic gas NO is the physiological activator of soluble guanylyl cyclase (sGC), thereby acting as a signaling molecule in the nervous and cardiovascular systems. Despite its rather poor sGC-activating property, CO has also been implicated as a physiologic...

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Detalhes bibliográficos
Main Authors: Friebe, A, Schultz, G, Koesling, D
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC452512/
https://ncbi.nlm.nih.gov/pubmed/9003762
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