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Tissue-nonspecific alkaline phosphatase as a target of sFRP2 in cardiac fibroblasts
Recent studies of myocardial infarction in secreted Frizzled-related protein 2 (sFRP2) knockout mice and our hamster heart failure therapy based on sFRP2 blockade have established sFRP2 as a key profibrotic cytokine in the heart. The failing hamster heart is marked by prominent fibrosis and calcific...
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| Publié dans: | Am J Physiol Cell Physiol |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Physiological Society
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4525083/ https://ncbi.nlm.nih.gov/pubmed/25972450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00009.2015 |
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