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Tissue-nonspecific alkaline phosphatase as a target of sFRP2 in cardiac fibroblasts

Recent studies of myocardial infarction in secreted Frizzled-related protein 2 (sFRP2) knockout mice and our hamster heart failure therapy based on sFRP2 blockade have established sFRP2 as a key profibrotic cytokine in the heart. The failing hamster heart is marked by prominent fibrosis and calcific...

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Bibliografiska uppgifter
I publikationen:Am J Physiol Cell Physiol
Huvudupphovsmän: Martin, Sean, Lin, Huey, Ejimadu, Chukwuemeka, Lee, Techung
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Physiological Society 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4525083/
https://ncbi.nlm.nih.gov/pubmed/25972450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00009.2015
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