Chemosensitization of multidrug resistant Candida albicans by the oxathiolone fused chalcone derivatives

Three structurally related oxathiolone fused chalcone derivatives appeared effective chemosensitizers, able to restore in part sensitivity to fluconazole of multidrug-resistant C. albicans strains. Compound 21 effectively chemosensitized cells resistant due to the overexpression of the MDR1 gene, co...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Ła̧cka, Izabela, Konieczny, Marek T., Bułakowska, Anita, Kodedová, Marie, Gašková, Dana, Maurya, Indresh K., Prasad, Rajendra, Milewski, Sławomir
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4525051/
https://ncbi.nlm.nih.gov/pubmed/26300857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2015.00783
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