Thalamic WNT3 Secretion Spatiotemporally Regulates the Neocortical Ribosome Signature and mRNA Translation to Specify Neocortical Cell Subtypes

Neocortical development requires tightly controlled spatiotemporal gene expression. However, the mechanisms regulating ribosomal complexes and the timed specificity of neocortical mRNA translation are poorly understood. We show that active mRNA translation complexes (polysomes) contain ribosomal pro...

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Publicat a:J Neurosci
Autors principals: Kraushar, Matthew L., Viljetic, Barbara, Wijeratne, H. R. Sagara, Thompson, Kevin, Jiao, Xinfu, Pike, Jack W., Medvedeva, Vera, Groszer, Matthias, Kiledjian, Megerditch, Hart, Ronald P., Rasin, Mladen-Roko
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2015
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524969/
https://ncbi.nlm.nih.gov/pubmed/26245956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0601-15.2015
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