Theoretical analysis of headache recurrence in patients administered triptans for migraine based on receptor occupancy

BACKGROUND: In this study, we retrospectively analyzed the relationship between headache recurrence and serotonin 5-HT(1B/1D) receptor occupancy (Φ(1B) and Φ(1D)). Triptans marketed in Japan (sumatriptan, zolmitriptan, eletriptan, rizatriptan, naratriptan) were investigated. METHODS: Receptor occupa...

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Publicado en:J Headache Pain
Autores principales: Tokuoka, Kentaro, Takayanagi, Risa, Toyabe, Mioko, Watanabe, Masayuki, Kitagawa, Yasuhisa, Yamada, Yasuhiko
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer Milan 2015
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524853/
https://ncbi.nlm.nih.gov/pubmed/26242873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10194-015-0558-9
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