Nutritional Status, Body Surface, and Low Lean Body Mass/Body Mass Index Are Related to Dose Reduction and Severe Gastrointestinal Toxicity Induced by Afatinib in Patients With Non-Small Cell Lung Cancer

BACKGROUND. The main reason for dose reduction of afatinib is gastrointestinal toxicity (GT). In a phase II study, we analyzed anthropometrical, nutritional, and biochemical factors associated with GT induced by afatinib. MATERIALS AND METHODS. Patients diagnosed with non-small cell lung cancer who...

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Detalhes bibliográficos
Publicado no:Oncologist
Main Authors: Arrieta, Oscar, De la Torre-Vallejo, Martha, López-Macías, Diego, Orta, David, Turcott, Jenny, Macedo-Pérez, Eleazar-Omar, Sánchez-Lara, Karla, Ramírez-Tirado, Laura-Alejandra, Baracos, Vickie E.
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2015
Assuntos:
Symptom Management and Supportive Care
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524769/
https://ncbi.nlm.nih.gov/pubmed/26173839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2015-0058
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