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Structure and Function in Homodimeric Enzymes: Simulations of Cooperative and Independent Functional Motions
Large-scale conformational change is a common feature in the catalytic cycles of enzymes. Many enzymes function as homodimers with active sites that contain elements from both chains. Symmetric and anti-symmetric cooperative motions in homodimers can potentially lead to correlated active site openin...
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| Publicat a: | PLoS One |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4524684/ https://ncbi.nlm.nih.gov/pubmed/26241964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133372 |
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