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Dimerization of TWIK-1 K+ channel subunits via a disulfide bridge.

TWIK-1 is a new type of K+ channel with two P domains and is abundantly expressed in human heart and brain. Here we show that TWIK-1 subunits can self-associate to give dimers containing an interchain disulfide bridge. This assembly involves a 34 amino acid domain that is localized to the extracellu...

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Bibliografische gegevens
Hoofdauteurs: Lesage, F, Reyes, R, Fink, M, Duprat, F, Guillemare, E, Lazdunski, M
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1996
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC452465/
https://ncbi.nlm.nih.gov/pubmed/8978667
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