A Murine Hypertrophic Cardiomyopathy Model: The DBA/2J Strain

Familial hypertrophic cardiomyopathy (HCM) is attributed to mutations in genes that encode for the sarcomere proteins, especially Mybpc3 and Myh7. Genotype-phenotype correlation studies show significant variability in HCM phenotypes among affected individuals with identical causal mutations. Morphol...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Zhao, Wenyuan, Zhao, Tieqiang, Chen, Yuanjian, Zhao, Fengbo, Gu, Qingqing, Williams, Robert W., Bhattacharya, Syamal K., Lu, Lu, Sun, Yao
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524617/
https://ncbi.nlm.nih.gov/pubmed/26241864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133132
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