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HIF1α is Necessary for Exercise-Induced Neuroprotection while HIF2α is Needed for Dopaminergic Neuron Survival in the Substantia Nigra pars compacta

Exercise reduces the risk of developing a number of neurological disorders and increases the efficiency of cellular energy production. However, overly strenuous exercise produces oxidative stress. Proper oxygenation is crucial for the health of all tissues, and tight regulation of cellular oxygen is...

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Pubblicato in:Neuroscience
Autori principali: Smeyne, Michelle, Sladen, Paul, Jiao, Yun, Dragatsis, Ioannis, Smeyne, Richard Jay
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524512/
https://ncbi.nlm.nih.gov/pubmed/25796140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2015.03.015
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