Combined treatment with olmesartan medoxomil and amlodipine besylate attenuates atherosclerotic lesion progression in a model of advanced atherosclerosis

INTRODUCTION: Besides their blood pressure-lowering effects, olmesartan medoxomil and amlodipine besylate exhibit additional anti-inflammatory mechanisms in atherosclerosic disease. Most of the studies investigating the effects of atherosclerosis focused on early atherosclerotic lesions, whereas les...

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Bibliographic Details
Published in:Drug Des Devel Ther
Main Authors: Sievers, Philipp, Uhlmann, Lorenz, Korkmaz-Icöz, Sevil, Fastner, Christian, Bea, Florian, Blessing, Erwin, Katus, Hugo A, Preusch, Michael R
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2015
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524379/
https://ncbi.nlm.nih.gov/pubmed/26251572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S85203
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