Nuclear import and cell cycle arrest functions of the HIV-1 Vpr protein are encoded by two separate genes in HIV-2/SIV(SM).

The vpr genes of human and simian immunodeficiency viruses (HIV/SIV) encode proteins which are packaged in the virus particle. HIV-1 Vpr has been shown to mediate the nuclear import of viral reverse transcription complexes in non-dividing target cells (e.g. terminally differentiated macrophages), an...

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Dettagli Bibliografici
Autori principali: Fletcher, T M, Brichacek, B, Sharova, N, Newman, M A, Stivahtis, G, Sharp, P M, Emerman, M, Hahn, B H, Stevenson, M
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1996
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC452436/
https://ncbi.nlm.nih.gov/pubmed/8947037
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