Ligand-regulated transport of the Menkes copper P-type ATPase efflux pump from the Golgi apparatus to the plasma membrane: a novel mechanism of regulated trafficking.

The Menkes P-type ATPase (MNK), encoded by the Menkes gene (MNK; ATP7A), is a transmembrane copper-translocating pump which is defective in the human disorder of copper metabolism, Menkes disease. Recent evidence that the MNK P-type ATPase has a role in copper efflux has come from studies using copp...

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Pubblicato in:	EMBO J
Autori principali:	Petris, M J, Mercer, J F, Culvenor, J G, Lockhart, P, Gleeson, P A, Camakaris, J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC452430/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8947031/
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