Head-to-Head Comparison of Poxvirus NYVAC and ALVAC Vectors Expressing Identical HIV-1 Clade C Immunogens in Prime-Boost Combination with Env Protein in Nonhuman Primates

We compared the HIV-1-specific cellular and humoral immune responses elicited in rhesus macaques immunized with two poxvirus vectors (NYVAC and ALVAC) expressing the same HIV-1 antigens from clade C, Env gp140 as a trimeric cell-released protein and a Gag-Pol-Nef polyprotein as Gag-induced virus-lik...

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Publicat a:J Virol
Autors principals: García-Arriaza, Juan, Perdiguero, Beatriz, Heeney, Jonathan, Seaman, Michael, Montefiori, David C., Labranche, Celia, Yates, Nicole L., Shen, Xiaoying, Tomaras, Georgia D., Ferrari, Guido, Foulds, Kathryn E., McDermott, Adrian, Kao, Shing-Fen, Roederer, Mario, Hawkins, Natalie, Self, Steve, Yao, Jiansheng, Farrell, Patrick, Phogat, Sanjay, Tartaglia, Jim, Barnett, Susan W., Burke, Brian, Cristillo, Anthony, Weiss, Deborah, Lee, Carter, Kibler, Karen, Jacobs, Bert, Asbach, Benedikt, Wagner, Ralf, Ding, Song, Pantaleo, Giuseppe, Esteban, Mariano
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2015
Matèries:
Vaccines and Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524234/
https://ncbi.nlm.nih.gov/pubmed/26041302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01265-15
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