Functional and Structural Characterization of Human V3-Specific Monoclonal Antibody 2424 with Neutralizing Activity against HIV-1 JRFL

The V3 region of HIV-1 gp120 is important for virus-coreceptor interaction and highly immunogenic. Although most anti-V3 antibodies neutralize only the sensitive tier 1 viruses, anti-V3 antibodies effective against the more resistant viruses exist, and a better understanding of these antibodies and...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Kumar, Rajnish, Pan, Ruimin, Upadhyay, Chitra, Mayr, Luzia, Cohen, Sandra, Wang, Xiao-Hong, Balasubramanian, Preetha, Nádas, Arthur, Seaman, Michael S., Zolla-Pazner, Susan, Gorny, Miroslaw K., Kong, Xiang-Peng, Hioe, Catarina E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524078/
https://ncbi.nlm.nih.gov/pubmed/26109728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01280-15
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