Molecular Signatures of Immune Activation and Epithelial Barrier Remodeling Are Enhanced during the Luteal Phase of the Menstrual Cycle: Implications for HIV Susceptibility

The variable infectivity and transmissibility of HIV/SHIV has been recently associated with the menstrual cycle, with particular susceptibility observed during the luteal phase in nonhuman primate models and ex vivo human explant cultures, but the mechanism is poorly understood. Here, we performed a...

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Pubblicato in:J Virol
Autori principali: Birse, Kenzie, Arnold, Kelly B., Novak, Richard M., McCorrister, Stuart, Shaw, Souradet, Westmacott, Garrett R., Ball, Terry B., Lauffenburger, Douglas A., Burgener, Adam
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2015
Soggetti:
Pathogenesis and Immunity
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524071/
https://ncbi.nlm.nih.gov/pubmed/26085144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00756-15
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