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Identification of the Receptor-Binding Domain of the Spike Glycoprotein of Human Betacoronavirus HKU1

Coronavirus spike (S) glycoproteins mediate receptor binding, membrane fusion, and virus entry and determine host range. Murine betacoronavirus (β-CoV) in group A uses the N-terminal domain (NTD) of S protein to bind to its receptor, whereas the β-CoVs severe acute respiratory syndrome CoV in group...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Qian, Zhaohui, Ou, Xiuyuan, Góes, Luiz Gustavo Bentim, Osborne, Christina, Castano, Anna, Holmes, Kathryn V., Dominguez, Samuel R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524053/
https://ncbi.nlm.nih.gov/pubmed/26085157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03737-14
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