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Trauma/hemorrhagic shock instigates aberrant metabolic flux through glycolytic pathways, as revealed by preliminary (13)C-glucose labeling metabolomics

BACKGROUND: Metabolic derangement is a key hallmark of major traumatic injury. The recent introduction of mass spectrometry-based metabolomics technologies in the field of trauma shed new light on metabolic aberrations in plasma that are triggered by trauma and hemorrhagic shock. Alteration in metab...

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Bibliographic Details
Published in:J Transl Med
Main Authors: D’Alessandro, Angelo, Slaughter, Annie L, Peltz, Erik D, Moore, Ernest E, Silliman, Christopher C, Wither, Matthew, Nemkov, Travis, Bacon, Anthony W, Fragoso, Miguel, Banerjee, Anirban, Hansen, Kirk C
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523956/
https://ncbi.nlm.nih.gov/pubmed/26242576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0612-z
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