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Plant Natural Products Calycosin and Gallic Acid Synergistically Attenuate Neutrophil Infiltration and Subsequent Injury in Isoproterenol-Induced Myocardial Infarction: A Possible Role for Leukotriene B4 12-Hydroxydehydrogenase?

Leukotriene B4 12-hydroxydehydrogenase (LTB4DH) catalyzes the oxidation of proinflammatory LTB4 into less bioactive 12-oxo-LTB4. We recently discovered that LTB4DH was induced by two different natural products in combination. We previously isolated gallic acid from Radix Paeoniae through a bioactivi...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Cheng, Yuanyuan, Zhao, Jia, Tse, Hung Fat, Le, X. Chris, Rong, Jianhui
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523677/
https://ncbi.nlm.nih.gov/pubmed/26265982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/434052
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