Rifamycin Derivatives Are Effective Against Staphylococcal Biofilms In Vitro and Elutable From PMMA

BACKGROUND: Local antimicrobial delivery through polymethylmethacrylate beads (PMMA), commonly vancomycin, is used for the treatment of contaminated open fractures but has limited activity against Staphylococcus aureus biofilms, which occur commonly in such fractures. Rifamycins have activity agains...

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Опубликовано в: :Clin Orthop Relat Res
Главные авторы: Sanchez, Carlos J., Shiels, Stefanie M., Tennent, David J., Hardy, Sharanda K., Murray, Clinton K., Wenke, Joseph C.
Формат: Artigo
Язык:Inglês
Опубликовано: Springer US 2015
Предметы:
Symposium: Research Advances After a Decade of War
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523531/
https://ncbi.nlm.nih.gov/pubmed/25896136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11999-015-4300-3
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