DAT isn’t all that: cocaine reward and reinforcement requires Toll Like Receptor 4 signaling

The initial reinforcing properties of drugs of abuse, such as cocaine, are largely attributed to their ability to activate the mesolimbic dopamine system. Resulting increases in extracellular dopamine in the nucleus accumbens (NAc) are traditionally thought to result from cocaine’s ability to block...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Psychiatry
Prif Awduron: Northcutt, A.L., Hutchinson, M.R., Wang, X., Baratta, M.V., Hiranita, T., Cochran, T.A., Pomrenze, M.B., Galer, E.L., Kopajtic, T.A., Li, C.M., Amat, J., Larson, G., Cooper, D.C., Huang, Y., O’Neill, C.E., Yin, H., Zahniser, N.R., Katz, J.L., Rice, K.C., Maier, S.F., Bachtell, R.K., Watkins, L.R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523496/
https://ncbi.nlm.nih.gov/pubmed/25644383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2014.177
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