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Hypusination of Eukaryotic Initiation Factor 5A via cAMP-PKA-ERK1/2 Pathway is required for Ligand-induced Downregulation of LH receptor mRNA Expression in the Ovary

Luteinizing hormone receptor (LHR) mRNA expression in the ovary is regulated post-transcriptionally by an LH receptor mRNA binding protein (LRBP). Eukaryotic initiation factor 5A (EIF5A), identified as an LRBP-interacting protein plays a crucial role in LHR mRNA expression. In this study, we have de...

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Detalhes bibliográficos
Publicado no:Mol Cell Endocrinol
Main Authors: Gulappa, Thippeswamy, Menon, Bindu, Menon, K. M. J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523407/
https://ncbi.nlm.nih.gov/pubmed/26116232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2015.06.014
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