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Inhibition of breast cancer progression by a novel histone deacetylase inhibitor, LW479, by down-regulating EGFR expression

BACKGROUND AND PURPOSE: Compounds targeting epigenetic events of tumours are likely to be an important addition to anticancer therapy. Histone deacetylase inhibitors (HDACI) have emerged as a promising novel class for therapeutic interventions associated with cancer, and many of them are currently i...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Li, Jingjie, Zhang, Tao, Yang, Feifei, He, Yuan, Dai, Fujun, Gao, Dan, Chen, Yihua, Liu, Mingyao, Yi, Zhengfang
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523338/
https://ncbi.nlm.nih.gov/pubmed/25884486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13165
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