Color-coding cancer and stromal cells with genetic reporters in a patient-derived orthotopic xenograft (PDOX) model of pancreatic cancer enhances fluorescence-guided surgery

Precise fluorescence-guided surgery (FGS) for pancreatic cancer has the potential to greatly improve the outcome in this recalcitrant disease. In order to achieve this goal, we have used genetic reporters to color code cancer and stroma cells in a patient-derived orthotopic xenograft (PDOX) model. T...

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Detalhes bibliográficos
Publicado no:Cancer Gene Ther
Main Authors: Yano, Shuya, Hiroshima, Yukihiko, Maawy, Ali, Kishimoto, Hiroyuki, Suetsugu, Atsushi, Miwa, Shinji, Toneri, Makoto, Yamamoto, Mako, Katz, Matthew H.G., Fleming, Jason B., Urata, Yasuo, Tazawa, Hiroshi, Kagawa, Shunsuke, Bouvet, Michael, Fujiwara, Toshiyoshi, Hoffman, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523223/
https://ncbi.nlm.nih.gov/pubmed/26088297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2015.26
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