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Pathogenic mechanisms and the prospect of gene therapy for choroideremia

INTRODUCTION: Choroideremia is a rare, X-linked disorder recognized by its specific ocular phenotype as a progressive degenerative retinopathy resulting in blindness. New therapeutic approaches, primarily based on genetic mechanisms, have emerged that aim to prevent the progressive vision loss. AREA...

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Podrobná bibliografie
Vydáno v:Expert Opin Orphan Drugs
Hlavní autoři: Dimopoulos, Ioannis S, Chan, Stephanie, MacLaren, Robert E, MacDonald, Ian M
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522943/
https://ncbi.nlm.nih.gov/pubmed/26251765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/21678707.2015.1046434
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