The 1.8 A crystal structure of human cathepsin G in complex with Suc-Val-Pro-PheP-(OPh)2: a Janus-faced proteinase with two opposite specificities.

The crystal structure of human neutrophil cathepsin G, complexed with the peptidyl phosphonate inhibitor Suc-Val-Pro-PheP-(OPh)2, has been determined to a resolution of 1.8 A using Patterson search techniques. The cathepsin G structure shows the polypeptide fold characteristic of trypsin-like serine...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Hof, P, Mayr, I, Huber, R, Korzus, E, Potempa, J, Travis, J, Powers, J C, Bode, W
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC452293/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8896442/
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