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Vaccine-elicited antibody that neutralizes H5N1 influenza and variants binds the receptor site and polymorphic sites

Antigenic drift of circulating seasonal influenza viruses necessitates an international vaccine effort to reduce the impact on human health. A critical feature of the seasonal vaccine is that it stimulates an already primed immune system to diversify memory B cells to recognize closely related, but...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Winarski, Katie L., Thornburg, Natalie J., Yu, Yingchun, Sapparapu, Gopal, Crowe, James. E., Spiller, Benjamin W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522792/
https://ncbi.nlm.nih.gov/pubmed/26170302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1502762112
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