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Zinc finger-mediated protein interactions modulate Ikaros activity, a molecular control of lymphocyte development.

The Ikaros gene, an essential regulator of lymphocyte differentiation, encodes, by means of differential splicing, protein isoforms with a distinct number of Kruppel-type zinc fingers organized in two domains. Deletion of the N-terminal zinc finger domain responsible for the sequence-specific DNA bi...

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Detalhes bibliográficos
Main Authors: Sun, L, Liu, A, Georgopoulos, K
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC452279/
https://ncbi.nlm.nih.gov/pubmed/8895580
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